Associations of microalbuminuria with brain atrophy and white matter hyperintensities in hypertensive sibships
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چکیده
منابع مشابه
White matter hyperintensities are associated with disproportionate progressive hippocampal atrophy
This study investigates relationships between white matter hyperintensity (WMH) volume, cerebrospinal fluid (CSF) Alzheimer's disease (AD) pathology markers, and brain and hippocampal volume loss. Subjects included 198 controls, 345 mild cognitive impairment (MCI), and 154 AD subjects with serial volumetric 1.5-T MRI. CSF Aβ42 and total tau were measured (n = 353). Brain and hippocampal loss we...
متن کاملWhite matter hyperintensities, cortisol levels, brain atrophy and continuing cognitive deficits in late-life depression.
BACKGROUND Cerebrovascular changes and glucocorticoid mediated hippocampal atrophy are considered relevant for depression-related cognitive deficits, forming putative treatment targets. AIMS This study examined the relative contribution of cortisol levels, brain atrophy and white matter hyperintensities to the persistence of cognitive deficits in older adults with depression. METHOD Thirty-...
متن کاملShorter telomere length is linked to brain atrophy and white matter hyperintensities.
BACKGROUND leukocyte telomere length (TL) is considered a marker of biological aging. Several studies have investigated the link between leukocyte TL and aging-associated functional attributes of the brain, but no prior study has investigated whether TL can be linked to brain atrophy and white matter hyperintensities (WMHs); two prominent structural manifestations of brain aging. METHODS we i...
متن کاملcomparison of brain white matter hyperintensities in methamphetamine and methadone dependent patients and healthy controls
background previous studies have proven the development of white matter hyperintensities (wmh) in methamphetamine and opioid users. opiates and methamphetamines (ma) are the most common addictive agents in iran. the adverse effects of drugs on the cns is of concern to specialists and researchers, and given that the neurotoxicity associated with methamphetamine is greater than opioids, it is hyp...
متن کاملWhite matter hyperintensities and normal-appearing white matter integrity in the aging brain
White matter hyperintensities (WMH) of presumed vascular origin are a common finding in brain magnetic resonance imaging of older individuals and contribute to cognitive and functional decline. It is unknown how WMH form, although white matter degeneration is characterized pathologically by demyelination, axonal loss, and rarefaction, often attributed to ischemia. Changes within normal-appearin...
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ژورنال
عنوان ژورنال: Journal of the Neurological Sciences
سال: 2008
ISSN: 0022-510X
DOI: 10.1016/j.jns.2008.03.009